R. Kruszyński, T. Bartczak, Z. Chilmonczyk
May 1, 2001
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Influential Citations
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Journal
Acta Crystallographica Section E-structure Reports Online
Abstract
A series of derivatives of 3-amino-2-oxazolidinone have been prepared. The 5-morpholinomethyl-3-(4-chlorobenzylideneamino)-2-oxazolidinone derivative is a potential psychotropic drug. Preliminary clinical data showed that the compound exhibits antidepressive activity in humans. The molecular geometry of the title compound, C15H18FN3O3, is similar to 5-morpholinomethyl-3-(4-chlorobenzylideneamino)-2-oxazolidinone. Two atoms of the title compound are disordered so that two different conformations of the oxazolidinone ring were found; one is a twist and the other is an envelope conformation. The crystal structure of title compound is formed by weak intermolecular C—H⋯O hydrogen bonds resulting in a two-dimensional infinite hydrogen-bond network.