Kristof J. Dubois, Christine Fannes, F. Compernolle
Feb 12, 1996
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron
Abstract
Abstract 4,6-Dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones obtained from cycloaddition of 2H-1,4-oxazin-2-ones and alkene compounds, undergo lactone cleavage with alcohols to yield 1,4,5,6-tetrahydro-5-hydroxy-6-oxo-2-pyridinecarboxylates which can be dehydrated or reduced to afford 1,6-dihydro-6-oxo-2-pyridine- or 6-oxo-2-piperidinecarboxylates.