A. V. Erkin, V. Krutikov
Nov 1, 2007
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Journal
Russian Journal of General Chemistry
Abstract
The reaction of 2-(2-acetoxyethyl)amino-4-chloro-6-methylpyrimidine with aromatic amines leads to a series of 4-arylamino-2-(2-acetoxyethyl)amino-6-methylpyrimidines. Deacetylation of these compounds proceeds in both acidic and basic media. Most of the arylaminopyrimides obtained exhibit a pronounced antituberculous effect.