V. Ravikumar, Z. Cheruvallath, D. L. Cole
Sep 9, 1996
Citations
0
Influential Citations
5
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract 4-Cyano-2-butenyl (CB) is a new type of protecting group for the intemucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild conditions by a δ-elimination pathway using aqueous ammonium hydroxide.