S. Arseniyadis, Francoise Richard, Carlos Mateos
Jan 1, 2021
Citations
0
Influential Citations
1
Citations
Journal
SynOpen
Abstract
Abstract 4-Cyano-3-oxotetrahydrothiophene (c-THT) has much more to offer than just a platform to various heterocyclic scaffolds. This solid, bench-stable and commercially available reagent can be readily transformed into thioglycolic acid and acrylonitrile upon simple addition of a hydroxide anion. This interesting feature enables its use as a particularly versatile acrylonitrile anion surrogate.