I. Ukrainets, V. Kravtsova, A. A. Tkach
Apr 30, 2010
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Influential Citations
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Journal
Chemistry of Heterocyclic Compounds
Abstract
Different variants of the preparation and procedures in the synthesis of a series of 1-R-3-(2-dialkyl-aminoethyl)-1H-quinazoline-2,4-dione hydrochlorides having a structural similarity to the 4-hydroxy-2-quinolinone anesthetic chinoxicaine are discussed. A comparative analysis of the biological properties of the synthesized compounds and the known local anesthetics chinoxicaine and lidocaine is reported.