Christopher F. Morrison, D. Burnell
Oct 15, 2001
Citations
0
Influential Citations
7
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The α-(hydroxymethyl)benzaldehyde derivative 2 has been synthesized by heating ynal 3 with diene 5 , which produced the α-(silyloxymethyl)benzaldehyde 6 by a Diels–Alder/ retro -Diels–Alder process, followed by methylation, thioacetalization, and removal of the silyl protecting group. Decarbonylation of α-(silyloxymethyl)benzaldehydes 6 and 10 takes place readily in the presence of zinc(II) chloride or para -toluenesulfonic acid.