Susan V. Cannon, A. Cummings, G. Teebor
Mar 30, 1988
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0
Influential Citations
96
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Quality indicators
Journal
Biochemical and biophysical research communications
Abstract
The enzymatic release of 5-hydroxymethylcytosine from T2 bacteriophage DNA was effected by an extract of calf thymus. Like the previously described 5-hydroxymethyluracil DNA glycosylase, 5-hydroxymethylcytosine DNA glycosylase was not detectable in bacterial extracts. The phylogenetic distribution of these activities indicates that their primary function is the maintenance of methylcytosine residues in differentiated tissue.