Youichi Sato, H. Shibata, N. Arakaki
Apr 1, 2004
Citations
0
Influential Citations
23
Citations
Journal
Antimicrobial Agents and Chemotherapy
Abstract
ABSTRACT We have demonstrated that 6,7-dihydroxyflavone by itself has only a weak antibacterial effect on methicillin-resistant Staphylococcus aureus (MRSA) but that at concentrations less than MIC it synergistically elevates the susceptibility of clinically isolated MRSA and methicillin-sensitive S. aureus strains to β-lactam antibiotics from 8- to 32,800-fold.