L. Widler, J. Green, M. Missbach
Mar 26, 2001
Citations
0
Influential Citations
42
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
7-Substituted-5-aryl-pyrrolo[2,3-d]pyrimidines have been prepared starting from alpha-bromoacetophenones. These compounds represent a novel class of potent inhibitors of the tyrosine kinase pp60(c-Src) with good specificity towards other tyrosine kinases (EGF-R, v-Abl).