R. G. Glushkov, L. Dronova, A. Elina
Nov 1, 1989
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Influential Citations
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Journal
Pharmaceutical Chemistry Journal
Abstract
In view of the fact that the basis of several antibacterial preparations is the nitroquinoline structure, we undertook the synthesis of l-ethyl-6-nitro-4-oxo-l,4-dihydroquinoline-3-carboxylic acids substituted at the 7-position by various amines or heteryl fragments. The starting compound for these syntheses was the ethyl ester of l-ethyl-6-nitro-7chloro-4-oxo-l,4-dihydroquinoline-3-carboxylic acid (I) [4].