Ikki Yonemura, Noriyuki Yasuda, Toshio Kawanami
2006
Citations
0
Influential Citations
0
Citations
Journal
Heterocycles
Abstract
Both (2R,5R)- and (2S,5S)-diethynylpyrrolidines were conveniently synthesized from 3,6-bis(mesyloxy)-1,7-octadiyne in optically pure forms via (R)-1-(4-methoxyphenyl)ethylamine-induced pyrrolidine ring formation, chromatographic separation of the corresponding diastereomers, and cleavage of the benzylic C-N bond.