Nitin S. Nandurkar, N. Kumar, O. Mukhina
Jan 14, 2013
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0
Influential Citations
21
Citations
Journal
ACS combinatorial science
Abstract
N-Furoylated L-threonine-, serine-, or cysteine-based aminoacetals are coupled with o-aminoketones or aldehydes to offer rapid access to diverse enantiopure polyheterocycles possessing conformationally locked aminoglycoside-containing molecular scaffolds. The key step involves photogeneration of azaxylylenes which undergo [4 + 4] or [4 + 2] cycloadditions to the tethered furoyl pendants.