V. Chagnault, P. Compain, K. Lewiński
Mar 19, 2009
Citations
0
Influential Citations
21
Citations
Journal
The Journal of organic chemistry
Abstract
A rapid and stereodivergent access to polyhydroxylated 10-azabicyclo[4.3.1]decanes as new calystegine analogues by way of a double benzotriazolyl/carbon nucleophile exchange followed by a ring-closing metathesis was achieved. Preliminary evaluation of the new compounds as glucocerebrosidase inhibitors was also performed.