C. Comoy, Estelle Banaszak, Y. Fort
Jun 19, 2006
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0
Influential Citations
24
Citations
Journal
Tetrahedron
Abstract
Abstract The synthesis of thieno[3,2- b ]pyridines was achieved using a three-step process allowing the construction of the thiophenic ring with 17–34% overall yields. The key step was the regioselective lithiation–bromination of the 3-methylthiopyridine induced by BuLi–LiDMAE superbase followed by Sonogashira coupling and halogenocyclization producing the fused heterocycles.