Santanu Hati, Pratip Kumar Dutta, S. Dutta
Jun 22, 2016
Citations
0
Influential Citations
28
Citations
Journal
Organic letters
Abstract
An exceptional oxone mediated tandem transformation of 2-aminobenzylamines to 2-substituted benzimidazoles is reported. It occurs at room temperature with aromatic, heteroaromatic, and aliphatic aldehydes. In this reaction initial condensation of 2-aminobenzylamine with appropriate aldehydes afforded a tetrahydroquinazoline intermediate which underwent oxone-mediated ring distortion to afford the desired compounds in moderate to excellent yields.