T. Nezu, O. Shimokawa
Oct 1, 2004
Citations
1
Influential Citations
6
Citations
Journal
Microbiology and Immunology
Abstract
Candida albicans ura3 mutants were found to produce large amounts of orotic acid when the growth medium was supplemented with sodium acetate. Experiments with 13C‐labeled acetate showed that the acetate served as a precursor of orotic acid. This system of acetate‐mediated production of orotic acid is similar to other documented microbial producers in yield but unique for its acetate requirement.