M. Raj, R. Goyal
Oct 1, 2017
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0
Influential Citations
15
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Journal
Sensors and Actuators B-chemical
Abstract
Abstract A sensitive and selective edge plane pyrolytic graphite sensor, modified using poly-melamine and poly-glutamic acid (p-Mel-Glu/EPPG) co-polymeric film through a single electropolymerization step, has been fabricated for the determination of 2-Thioxanthine (2-TX). The extremely sensitive interlinked polymeric film formed at the surface of pyrolytic graphite was characterized by using Field Emission Scanning Electron Microscopy, Electrochemical Impedance Spectroscopy, Cyclic Voltammetry and Square Wave Voltammetry techniques. The sensing surface exhibited electrocatalytic effects towards the oxidation of 2-TX, by displaying the significant enhancement in the sensitivity in terms of an increase in the peak current and shift of the peak potential to less positive potentials. The proposed method exhibited linear relation of the peak current in the concentration range of 0.5–150 μM and the limit of detection and limit of quantification were found as 1.0 nM and 3.4 nM, respectively. The developed approach has successfully been applied for the quantification of 2-TX in the presence of common interferents present in the urine.