W. Moolenaar, O. Kranenburg, F. Postma
Apr 1, 1997
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Influential Citations
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Quality indicators
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Current opinion in cell biology
Abstract
Lysophosphatidic acid (LPA) is a serum-borne phospholipid that activates a specific G protein coupled receptor to evoke multiple cellular responses. Recent work has identified two cDNAs encoding putative LPA receptors, various LPA-like agonists that act on distinct receptors, and new pathways that link the receptor(s) to such diverse events as Ras signalling, cytoskeletal remodelling and membrane depolarization.