Soonho Hwang, H. Park, Yongseok Kwon
Nov 10, 2014
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0
Influential Citations
4
Citations
Journal
RSC Advances
Abstract
A convenient acid-promoted cyclization protocol for the formation of azaheterocycles from amino alcohols is described. The reaction involves the use of N,N-dimethylacetamide dimethyl acetal (DMADA) as the activating reagent of the hydroxyl group. Using this protocol, pyrrolidines or piperidines with various substituents can be synthesized in good to high yields.