L. S. M. Miranda, B. Marinho, S. Leitão
Mar 22, 2004
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Influential Citations
24
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Journal
Bioorganic & medicinal chemistry letters
Abstract
We described in this paper the first synthesis to the (+/-) cis (6-ethyl-tetrahydropyran-2-yl) formic acid (1) using the very efficient Prins cyclization reaction as strategy to construction of its tetrahydropyran skeleton. This new compound presented a significant antinociceptive property by the tail-flick model.