E. Goldberg, V. A. Eshchenko, V. Bovt
1991
Citations
0
Influential Citations
17
Citations
Quality indicators
Journal
Experimental pathology
Abstract
Diabetogenic and acidotropic effects of dithizone, 8-(p-toluenesulfonylamino)-quinoline and 8-(benzenesulfonylamino)-quinoline were studied in experiments on cats, rabbits, golden hamsters and mice. Selective damage of insulin producing cells, phase glycemic fluctuations and permanent diabetes development were shown to be connected with chelator zinc binding in the lysosome-segregation apparatus of these cells.