Cuiying Chen, Baoli Sun, W. Guan
2016
Citations
0
Influential Citations
30
Citations
Journal
Aquaculture
Abstract
Abstract This study was conducted to investigate the effects of dietary linolenic acid (LNA) on non-specific immunity and anti-inflammatory responses in juvenile Nile tilapia, Oreochromis niloticus . Purified ethyl linolenate was added to the basal diet to formulate seven isoproteic and isolipidic diets containing 0.00, 0.10, 0.32, 0.63, 0.98, 1.56 and 2.04% LNA of dry weight, respectively. All diets contained similar amounts of 18:2n-6 (0.61% of dry weight) from purified ethyl linoleate. Basal diet without LNA was considered as a control. Fish were fed experimental diets for 10 weeks. The results showed that amounts of LNA as well as eicosapentaenoic acid, docosahexaenoic acid and even arachidonic acid in head kidney macrophages showed strong positive curvilinear relationships with dietary LNA levels. No significant differences were observed in serum lysozyme and superoxide dismutase activities among dietary treatments ( P P P P Statement of relevance To our knowledge, this is the first study to provide specific evidence for the anti-inflammatory effect of linolenic acid in juvenile tilapia. Moreover, this study helps to further confirm the dietary requirement of linolenic acid for juvenile tilapia.