E. Ochiai, T. Okamoto
Jul 20, 1959
Citations
1
Influential Citations
6
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
The presence of α-methylenecyclohexanol grouping in ignavine or des-N-methyl-anhydroignavinol was proved by rearrangement reaction to ketone. Oxidative cleavage of the cyclohexanol ring in des-N-methylanhydroignavinol gave a dicarboxylic and one of the carboxyl groups in this acid was confirmed as tertiary. α-Glycol group which is another functional group in des-N-methylanhydroignavinol was also cleaved by oxidation to give a dicarboxylic acid and the glycol was proved to exist at carbons γ ond δ to the nitrogen.