H. Wiseman, M. Laughton, H. Arnstein
Apr 24, 1990
Citations
0
Influential Citations
75
Citations
Quality indicators
Journal
FEBS Letters
Abstract
The anti‐oestrogen drug tamoxifen is an inhibitor of lipid peroxidation in rat liver microsomes and in phospholipid liposomes. Its cis isomer and N‐desmethyl form are weaker inhibitors, but 4‐hydroxytamoxifen is much more powerful. It is possible that the antioxidant property of tamoxifen might contribute to its biological actions.