J. Desroches, P. Champagne, Yasmine Benhassine
Feb 10, 2015
Citations
0
Influential Citations
21
Citations
Journal
Organic & biomolecular chemistry
Abstract
The Friedel-Crafts benzylation of arenes using benzyl alcohols activated in situ with XtalFluor-E is described. A wide range of 1,1-diarylmethanes and 1,1,1-triarylmethanes were prepared under experimentally simple and mild conditions, without the need for a transition metal or a strong Lewis acid. Notably, the reactivity observed demonstrates the potential of XtalFluor-E to induce C-OH bond ionization and SN1 reactivity of benzylic alcohols.