D. S. Ugdyzhekova, A. Krylatov, N. A. Bernatskaya
Feb 1, 2002
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1
Influential Citations
18
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Journal
Bulletin of Experimental Biology and Medicine
Abstract
We studied the possibility of decreasing the area of ischemic necrosis during myocardial infarction with HU-210, a selective cannabinoid receptor agonist. Activation of cannabinoid receptors with HU-210 had practically no effect on collateral blood flow in the myocardium, but considerably decreased the area of necrosis. There results indicate that cannabinoid receptor agonist HU-210 possesses cardioprotective activity and delays the formation of necrotic zones during coronary occlusion and reperfusion.