I. Galpin, P. Gordon, R. Ramage
1976
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron
Abstract
Abstract A study is made of the effect of 1-hydroxybenzotriazole on μ-oxo-bis-[tris(dimethylamino)-phosphonium]-bis-tetrafluoroborate 1 during amide bond formation. The reagent 1 is used to activate phenylhydroxamic acid towards a Lossen-type rearrangement and bring about Beckmann rearrangement of ketoximes under mild conditions. Both syn - and anti -benzaldoxime give benzonitrile by elimination.