M. Eto, S. Okabe, Y. Ozoe
Aug 1, 1977
Citations
2
Influential Citations
43
Citations
Journal
Pesticide Biochemistry and Physiology
Abstract
Abstract O,S -Dimethyl phosphoramidothiolate, the insecticide methamidophos, is converted oxidatively into a potent anti-cholinesterase agent by the action of m -chloroperbenzoic acid. The active intermediate is not stable enough to be isolated. From some chemical evidence, the sulfoxide, i.e., dimethyl phosphoramidothiolate S -oxide, is most probably the active intermediate. A similar activation may occur by biological oxidation.