M. S. Jensen, H. Mutsaers, S. J. Tingskov
May 20, 2019
Citations
2
Influential Citations
40
Citations
Quality indicators
Journal
Acta Physiologica (Oxford, England)
Abstract
Renal fibrosis plays a pivotal role in the development and progression of chronic kidney disease, which affects 10% of the adult population. Previously, it has been demonstrated that the cyclooxygenase‐2 (COX‐2)/prostaglandin (PG) system influences the progression of renal injury. Here, we evaluated the impact of butaprost, a selective EP2 receptor agonist, on renal fibrosis in several models of kidney injury, including human tissue slices.