M. Carmellino, G. Pagani, M. Pregnolato
1994
Citations
0
Influential Citations
24
Citations
Quality indicators
Journal
European Journal of Medicinal Chemistry
Abstract
Abstract Fluoro and trifluoromethyl derivatives of 1,2-benzisothiazol-3(2H)-ones and the 2,2′-dithiobis(benzamides) have been prepared and their antifungal and antibacterial activity evaluated. Several compounds were found highly active against fungi and Gram-positive microorganisms and a few derivatives displayed some activity against Gram-negative strains. Structure-activity relationships are proposed.