Lakdasa D. Premawardhana, I. Ismail, D. Riad-fahmy
May 1, 1994
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0
Influential Citations
5
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Quality indicators
Journal
Clinical Endocrinology
Abstract
OBJECTIVES Pirenzepine, a selective muscarinic cholinergic antagonist, reduces plasma insulin and plasma glucose responses to a mixed meal in a dose dependent fashion in normals and in patients with non‐insulin dependent diabetes. We have studied the effects of pirenzepine on plasma insulin, plasma glucose, growth hormone (GH), androstenedione, testosterone, insulin‐like growth factor‐I (IGF‐I) and IGF binding protein 1 (IGFBP‐1) responses to a mixed meal in obese clinically hyperandrogenic women with the polycystic ovary syndrome.