D. Brigden, P. Fiddian, A. Rosling
Nov 1, 1981
Citations
0
Influential Citations
44
Citations
Quality indicators
Journal
Antiviral research
Abstract
A review of the literature on acyclovir (Zovirax), a new antiherpes drug, with particular activity against herpes simplex virus types I and II and also against varicella-zoster, Epstein-Barr, cytomegalo and herpes B viruses, is presented. The article deals with 'in vitro' and 'in vivo' efficacy in animals, animal toxicity, latency and resistance, the mechanism of action and early clinical experience.