G. Hanson, J. Baran, T. Lindberg
1986
Citations
0
Influential Citations
24
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Aldol condensation of lithioethyl acetate with Boc- lfsf -prolinal proceeds stereoselectively to give R,S diastereomer 2. Acidolysis of the Boc group and lactamization gives crystalline 3 which possesses the pyrrolizidine alkaloid skeleton. Saponification and acidolysis of 2 yields 7, a novel GABA analogue.