Sung Soo Kim, J. Kwak
Jan 2, 2006
Citations
0
Influential Citations
59
Citations
Journal
Tetrahedron
Abstract
Abstract Trimethylsilyl cyanide asymmetrically adds to various ketones by catalysis of 1 /triphenylphosphine oxide. This is a double activation where 1 acts as Lewis acid and Ph3PO Lewis base. Various ketones were subjected to the enantioselective addition so as to give up to 92% ee and >90% yield.