M. Bannai, Nobuhiro Kawai, K. Nagao
Mar 1, 2011
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Journal
Psychiatry and Clinical Neurosciences
Abstract
Aim: Glycine, one of the non‐essential amino acids, has been reported to be effective in reducing negative symptoms of schizophrenia. Recently, we found that glycine improves subjective sleep quality in humans. The aim of this study was to investigate the effects of oral glycine administration on endogenous 5‐hydroxytryptamine (5‐HT) and dopamine in the prefrontal cortex (PFC) of living rats.