Zhao Yun
2008
Citations
0
Influential Citations
0
Citations
Journal
Fine Chemical Intermediates
Abstract
Nolatrexed is a new non-classical, water-soluble and high-efficient thymidylate synthase (TS) inhibitor. and has now been attracting great attentions. The latest progress in the synthetic technology of nolatrexed was reviewed in the paper. The merits and limitations of every synthetic technology were analyzed. The prospect and future development trend of the synthetic technology of nolatrexed were proposed as well.