Feng Yan, Cai Shuang, Wu Wen
2020
Citations
0
Influential Citations
5
Citations
Journal
Chinese Journal of Organic Chemistry
Abstract
N -Methylation of amines and imines is one of the most important reactions for C — N bond formation. It is widely utilized for both laboratary research and industrial applications. Traditional methylation reactions involve the use of flammable, explosive and toxic starting materials. In contrast, newly developed methods have overcome this point and provide a mild strategy. In this transformation, C1 carbon source for the methyl group is important which determines the type of catalyst, reaction conditions and substrate scope. Herein, the research progress for the N -methylation of amines and imines is summarized based on different C1 carbon source.