M. Gouda, G. G. El-Bana
May 9, 2023
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Journal
Mini-Reviews in Organic Chemistry
Abstract
This review described the preparation of 2-(piperazin-1-yl) quinoline derivatives from 2-haloquinolines and anilides, which underwent alkylation, arylation, acylation, and reductive amination to form the 2-piprazinoquinolines. 2-(Piperazin-1-yl) quinoline used as building blocks for the synthesis of polyfunctionalized heterocyclic compounds with pharmacological interest.