Liu Wenba
2014
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Journal
Progress in Pharmaceutical Sciences
Abstract
Nervonic acid is one of core natural ingredients with special biological function in brain nerve cells and tissues, which plays a crucial role in human health, especially in brain health. The advances in research on the biological function and mechanism of action of nervonic acid, its preparation(including extraction and separation from acer truncatum oil, chemical synthesis and transgenic biosynthesis) and its applications in the prevention and treatment of encephalopathy(including multiple sclerosis, adrenoleukodystrophy, Zellweger syndrome, Alzhemier's disease and so on) were reviewed.