Zhu Bao-cheng
2003
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Journal
Journal of Biology
Abstract
D-hydroxyphenylglycine was the most important precursor used for the synthesis of semisynthetic penicillin and cephalosporin.The microbial enzymatic synthesis of D-p-hydroxyphenylglycine were reviewed.The screening methods to obtain the strains which can produce D-hydantoinase and D-carbamoylase were introduced.Furthermore,the advances on genetic engineering were discussed.