B. Dalhus, C. Görbitz
Sep 15, 1999
Citations
1
Influential Citations
20
Citations
Journal
Acta Crystallographica Section C-crystal Structure Communications
Abstract
The amino acids L-leucine (L-Leu) and L-valine (L-Val) have been cocrystallized with D-aminobutanoic acid (D-Abu), D-2-aminopentanoic acid (D-Nva) and D-methionine (D-Met) to form six complexes, L-Leu:D-Abu, C 6 H 13 NO 2 .C 4 H 9 NO 2 , L-Leu:D-Nva, C 6 H 13 NO 2 .C 5 H 11 -NO 2 , L-Leu:D-Met, C 6 H 13 NO 2 .C 5 H 11 NO 2 S, L-Val:-D-Abu, C 5 H 11 NO 2 .C 4 H 9 NO 2 , L-Val:D-Nva, C 5 H 11 NO 2 .-C 5 H 11 NO 2 and L-Val:D-Met, C 5 H 11 NO 2 .C 5 H 11 NO 2 S. A fourth L-Leu complex, with D-Val, C 6 H 13 NO 2 .C 5 H 11 -NO 2 has also been studied. The crystals of these amino acid complexes are all divided into distinct hydrophilic and hydrophobic layers. The D- and L-amino acids are all related by pseudo-inversion in the L-Leu complexes and by pseudo-glide planes in the L-Val series. Similarities and differences in the crystal packing and molecular conformations of L-Leu/L-Val, as well as of the partner molecules, are discussed.