Ajay Singh, Karthik V Iyer, Anshu Gupta
Jan 1, 2018
Citations
0
Influential Citations
2
Citations
Journal
Saudi Journal of Anaesthesia
Abstract
In a study conducted by Ding et al., the authors found that mice who were treated with ciproxifan had improved postanesthesia cognitive memory performance when exposed to isoflurane for about 2 h.[5] The drug at a dose of 1–3 mg/kg intravenous was shown to reverse cognitive changes developed after 24 h exposure in a span of 30 min after injection. Theoretically, ciproxifan appears as a drug that could be either used for prophylaxis for preventing or for treating AIDN. Further studies are required to establish its safety and efficacy for use in humans.