K. Kumar, S. Chamakuri, Peddy Vishweshwar
Jun 23, 2010
Citations
0
Influential Citations
24
Citations
Journal
Tetrahedron Letters
Abstract
Abstract AlCl3 facilitated C–C bond forming reaction between 4-chloro-thieno[2,3-d]pyrimidines and (hetero)arenes affording a direct and single-step method for the synthesis of 4-(hetero)aryl substituted thieno[2,3-d]pyrimidines. A number of novel thienopyrimidines were prepared in good to excellent yields using this methodology. The molecular structure of a representative compound was established unambiguously by single crystal X-ray diffraction.