G. H. Svoboda, N. Neuss, M. Gorman
Sep 27, 2006
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0
Influential Citations
138
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Quality indicators
Journal
Journal of the American Pharmaceutical Association. American Pharmaceutical Association
Abstract
As part of continuing study of alkaloid-bearing members of the family Apocynaceae , we have undertaken a detailed phytochemical investigation of the pantropical plant Vinca rosea Linn. (1). Twelve crystalline compounds have been obtained and characterized. Details of the procedure leading to the preparation of pure substances are described. Two of these alkaloids, leurosine and vincaleukoblastine, possess activity against P-1534 leukemia in mice.