V. A. Krasovskii, S. I. Burmistrov
1965
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Journal
Chemistry of Heterocyclic Compounds
Abstract
Alkylation of 2-amino-4,5-dimethylthiazole with isopropanol and cyclohexanol in 85% sulfuric acid gives good yields of isopropylamino- and 2-cyclohexylamino-4,5-dimethylthiazole. The structures of the products are demonstrated by reverse synthesis from 3-chlorobutanone and substituted thioureas.