T. Hiyama, Hajime Yamamoto, K. Nishio
Dec 1, 1979
Citations
0
Influential Citations
14
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Treatment of bromocyclopropanes with excess dibutylcopperlithium in tetrahydrofuran at −48 °C gives the respective organocopper intermediates which upon quenching with excess alkyl halides afford alkylated cyclo-propanes with retention of the configuration. This process is applied to the synthesis of methyl cascarillate. Bromoarenes are also reduced with dibutylcopperlithium and allylarenes are prepared therefrom.