Sandeep Goyal, Anamika Thakur, Ratnesh K. Sharma
Aug 1, 2016
Citations
0
Influential Citations
6
Citations
Journal
Asian Journal of Organic Chemistry
Abstract
(S)-4-Isopropyl-1-((R)-1-phenylethyl)imidazolidin-2-one was evaluated as a chiral auxiliary for asymmetric acetate and propionate Mannich-type reactions, by generation ofthe titanium enolates, affording excellent yields and stereoselectivities. The application of the auxiliary was exemplified in the stereoselective synthesis of ezetimibe.