T. V. Pravdich-Neminskaya, A. P. Kachkov
2004
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0
Influential Citations
4
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Journal
Bulletin of Experimental Biology and Medicine
Abstract
The effect of allo-ocimene, one of the carotenoid polyenes, which stimulate metabolism in vivo and are active agents promoting normalization of trophic disturbances, on the healing of experimental soft tissue wounds by second intention was studied. Allo-ocimene increased the intensity of healing processes in skin and skin-muscle wounds, in some cases shortened the time required for complete healing, had an antiinflammatory action on the wound and neighboring zones, abolished or reduced edema, hyperemia, laceration, and hemorrhage, and prevented the development of manifestations of acute inflammation. The methods of quantitative analysis of these effects of allo-ocimene used in these experiments provide a method of evaluating its beneficial action on tissue nutrition in the course of wound healing.