Qing Zhu, Matthew S. Tremblay
Dec 15, 2006
Citations
0
Influential Citations
6
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
Iodotrimethylsilane (TMSI), routinely used for the dealkylation of ethers and esters, has been found to efficiently convert allyl and benzyl phosphotriesters into the corresponding iodides under mild, Bronsted-neutral conditions. In contrast, alkyl and aryl phosphotriesters were dealkylated to the corresponding phosphates under identical conditions.